Vaginal Cancer Risk Factors  

Many factors are suspected in the development of vaginal cancer; the most common include: 

• smoking 
• multiple sexual partners (the fact that it increases your risk of STDs) 
• history of cervical cancer 
• having had a hysterectomy 
• having had radiation therapy to the pelvic area 
• Age – squamous cell vaginal canceris more common in women aged 50 or over 
• history of human papillomavirus (HPV) disease such as genital warts 
• certain precancerous conditions in vagina such as vaginal intraepithelial neoplasia (VAIN) 
• having taken diethylstilbestrol (DES) during pregnancy 
• Personal history of gynecologic cancer, especially cervical cancer.  

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