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Myeloma Symptoms 

Multiple myeloma can remain asymptomatic for many years; the disease continues its physiological damage without causing noticeable symptoms. In most cases, signs and symptoms begin to emerge after a long period after the tumor is advanced. 

Many patients find out they have multiple myeloma during a routine blood test or a diagnostic for another medical condition. As myeloma affects the bones of the spine, the first symptom is often a pain in the back, ribs, neck or pelvis.  

The most common multiple myeloma symptoms include:  

  • weakness and fatigue 
  • easy bruising 
  • paleness  
  • weight loss  
  • blurred vision  
  • unexplained bone fractures  
  • leg weakness or numbness 
  • excessive thirst and urination 
  • loss of appetite 
  • nausea and vomiting  
  • loss of sensation  
  • headache and dizziness  
  • purple patches under the skin  
  • unusual nose or gums bleeding  
  • confusion, disorientation, difficulty concentrating   
  • frequent infections, mostly pneumonia, sinusitis, bladder or kidney infections, skin infections 
  •  muscle weakness associated with decreased muscle reflexes.  



            Myeloma Risk Factors                                    Myeloma Complications