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Lymphoma Causes & Risk Factors 

The causes of lymphoma are not well known, but some factors seem to have a role in its development: 

  • Immunosuppressive therapy - immunosuppressive treatment can lead to deficiency of the immunological functions and the development of many types of cancer including lymphoma. 
  • Family history of lymphoma - if your parents had/ have lymphoma, you are more at risk to develop it.  
  • Toxic exposure - lymphoma can occur due to exposure to certain toxic chemicals such as dioxins, pesticides, benzene, and organic solvents. 
  • Virus - Epstein-Barr virus may play a role in the occurrence of malignant lymphoma. Its role in cancer development has been established for the first time in Africa. Epstein-Barr virus is also incriminated in cancer of the nasopharynx (nasopharyngeal cancer).
  • HIV / AIDS - the acquired immunodeficiency syndrome (AIDS) may also facilitate the occurrence of non-Hodgkin's lymphoma. In addition, the following viruses can also be involved in the occurrence of the disease: 

a)     hepatitis C virus (HCV) 

b)    helicobacter pylori (H. pylori

c)    human herpesvirus 6 and Human herpesvirus 8 (HHV 6 and HHV 8) 

d)    Helicobacter pylori Human T lymphoma/leukemia virus (HTLV-1).


  • Immunodeficiency - certain immune disorders are able to cause hyperplasia of your bone marrow and in a number of cases, give rise to a lymphoid tumor. Some of those diseases include:  

a)    lupus  

b)    sarcoidosis 

c)    Celiac disease 

d)    Sj√∂gren's Syndrome  

e)    hashimoto thyroiditis  

f)    rheumatoid arthritis 

g)    Scleroderma.


Lymphoma Statistics                                     Warning signs and Symptoms