Warnings: There are many side effects that are associated with Cytoxan, all of which you should report to
your doctor. Although Cytoxan is usually used as a cancer medication, it can also increase your chances of
developing other cancers. You should not plan on getting pregnant while on this medication, because it may harm the
fetus. You may also lose fertility over extended use of Cytoxan.
Indications: This medication is most commonly
recommended in cancer treatment. It is used to treat different types of leukemia, lymphoma, and various types of
cancers affecting bones, blood, and nerves. However, it can be used to treat other types of cancers and some
other diseases as well. One of the non-cancerous diseases that Cytoxan is most commonly used to treat is
neuphrotic syndrome, a group of symptoms often characterized by presence of protein in the urine, low blood protein
levels, high cholesterol levels, high triglyceride levels, and
works to slow, and sometimes stop the growth of cancerous cells, and other fast-growing cells such as those in
your immune system, which makes it useful in treating neuphrotic syndrome. Cytoxan can also be used under
doctor’s supervision to treat some other non-cancerous diseases, but should be used carefully.
Most common malignancies that Cytoxan is used to treat include:
lymphomas and non-Hodgkin's lymphomas
lymphocytic leukemia (CLL), chronic myelocytic leukemia (CML), acute myelocytic
leukemia (AML), acute lymphocytic leukemia (ALL)
Cytoxan can be taken by mouth
in tablet form or by injection into a vein. But the medication is almost always comes as a tablet, and you may be
prescribed a long-term treatment of the medication, or only a small amount, depending on what you are trying to
treat and various others factors. You will take one tablet every day, preferably at the same time every day. You
should never take more or less than what is prescribed, and if you miss a dose, you should only take your missed
dose if your next dose will not be taken soon, and should never double a dose. You should also never quit taking
this medication without talking to a doctor, even if you are experiencing side effects.
The injection of Cytoxan is done in a hospital or a medical facility equipped for its preparation. The drug must be
prepared and administered by specialists in oncology or hematology, or nurses who have experience in administering
It is important that you drink plenty of fluids during the treatment. Drink at least 8 ounce glasses of fluid every
day to help you urinate frequently; this prevents the drug from damaging your kidneys and other organs in your
recommended for all drugs, Keep Cytoxan out of children reach.
Store the medication at room temperature below 25 degrees Celsius (77 degrees Fahrenheit), and strictly away
from temperatures exceeding 30 degrees Celsius. Always store Cytoxan away from moisture and heat. Discard any unused doses after the expiration date. Talk
to your pharmacist about the proper disposal of the medication.
Cytoxan is taken by injection in hospital, the administration is done by professionals which reduce or
eliminate the of overdose. When the drug is taken by mouth chance of overdose increases; either voluntary or
involuntary, it may happen that some patients take higher dose. Cytoxan overdose can cause severe and even fatal
health problems. An accidental overdose in elderly and especially among young children can lead to
If you think you have taken an overdose of Cytoxan, contact a poison control center or go to an emergency as soon
If you are recommended to take Cytoxan by mouth in tablet form, you can easily forget to take it. If you forgot to
take the drug for less than 12 hours, take the usual dose. Beyond 12 hours, it is better to wait for the next dose
to continue taking the medication as usual; do not double.
There are few contraindications associated with Cytoxan, as most patients who are prescribed this medication
are usually in poor health to begin with, but you should be sure to talk to your doctor about your past your health
issues and your current health before starting any medication.
should be used with precautionin in the following conditions:
to cyclophosphamide or any of its ingredients
white blood cell count
Interactions: Cytoxan reacts with many medications, including a
variety of other cancer and cancer-related medications (allopurinol, cortisone acetate, and doxorubicin, for
example), a seizure medication (phenobarbital), and over the counter drugs (such as hydrocortisone). You should
be sure to tell your doctor about every medication and supplement, whether prescription or over-the-counter,
that you are currently taking or are planning to take. This will help your doctor to determine which medications
are safe for you to take.
interact with certain substances; talk to your doctor before taking these products:
St. John's wort
- anti anemia drugs such as filgrastim and pegfilgrastim
attacking cancer cells, Cytoxan also damages healthy cells that multiply rapidly in the body, which can
cause various adverse effects in some patients. Some Cytoxan side effects include:
If the side
effects above become severe or persist for long, contact your oncologist. In addition, contact your doctor
immediately if you experience any of these symptoms:
shortness of breath or difficulty
unusual bruising or bleeding
swelling of the feet or ankles
Bloody or red urine